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Novel Micro-optical structures on optical fiber tip with two-photon lithography

Project

Project Details

Program
BioScience
Field of Study
​Electrical Engineering, physics
Division
Biological and Environmental Sciences and Engineering
Faculty Lab Link
https://www.kaust.edu.sa/en/study/faculty/carlo-liberale

Project Description

Optical fibers are nowadays an ubiquitous core element of telecommunication systems, new laser technologies and biomedical devices. Manufacturing techniques for optical fibers have been developed and refined in order create manifold geometries and optical properties (e.g.Dual clad fibers, fiber bundles, Photonic Crystal Fibers, to name a few). Yet the capability to fabricate complex miniaturized structures integrated with optical fibers to realize important optical functions (like beam shaping, beam deflection, fiber optical tweezers, etc.) has been demonstrated only very recently.The project will focus on the fabrication of optical wave-guiding structures on the tip of optical fibers exploiting to flexibility, resolution and 3D fabrication capability of Laser Direct Writing based on Two-Photon Lithography (TPL).​ ​​​​

About the Researcher

Carlo Liberale
Research Associate Professor, Bioscience
Biological and Environmental Science and Engineering Division

Affiliations

Education Profile

  • Ph.D., University of Pavia, Italy, 2004
  • M.Sc., University of Pavia, Italy, 2000

Research Interests

Prof. Liberale's research interests are focused on developing and applying label-free chemical imaging techniques based on vibrationalA spectroscopy (Infrared and Raman micro-spectroscopy) and multi-photon processes (Coherent Raman Microscopy, SHG). One of the mainA aims of this research activity is to unveil specific bio-chemical signatures of cancer stem cells, with a particular focus on understanding theA dysregulation of their lipid metabolism. He is also interested on using high-resolution 3D printing based on Direct Laser Writing for the fabrication of novel micro-optics, towardsA the miniaturization of complex optical systems, and of smart micro-/nano-structures to be used as a probe in nanoscale imaging. ThisA research activity takes advantage from an integrated approach that combines design, micro/nanofabrication and optical techniques.a€‹

Selected Publications

  • Extended field-of-view ultrathin microendoscopes for high-resolution two-photon imaging with minimal invasiveness A Antonini, A Sattin, M Moroni, S Bovetti, C Moretti, F Succol, A Forli, D Vecchia, V P Rajamanickam, A Bertoncini, S Panzeri, C Liberale, T Fellin, eLife 9:e58882 (2020)
  • 3D printed waveguides based on Photonic Crystal Fiber designs for complex fiber-end photonic devices, A Bertoncini, C Liberale, Optica 7 (11), 1487-1494 (2020)
  • Fingerprinta€toa€CH stretch continuously tunable high spectral resolution Stimulated Raman Scattering microscope, S P Laptenok, V P Rajamanickam, L Genchi, T Monfort , Y Lee, I I Patel, A Bertoncini, C Liberale, Journal of Biophotonics 12(9) e201900028 (2019)
  • Lipid droplets: a new player in colorectal cancer stem cells unveiled by spectroscopic imaging, L Tirinato, C Liberale, S Di Franco, P Candeloro, A Benfante, R La Rocca, L Potze, R Marotta, R Ruffilli, V P Rajamanickam, M Malerba, F De Angelis, A Falqui, E Carbone, M Todaro, J Medema, G Stassi, E Di Fabrizio, Stem Cells 33 (1), 35-44 (2015)
  • Miniaturized all-fibre probe for three-dimensional optical trapping and manipulation, C Liberale, P Minzioni, F Bragheri, F De Angelis, E Di Fabrizio, I Cristiani, Nature Photonics 1 (12), 723-727 (2007)

Desired Project Deliverables

​Learn Two-Photon Lithography. Design structures using wave-optics propagation software. Fabricate structures on optical fibers. Measurements to assess optical function of fabricated structures.​
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