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Project Details

Program
Electrical Engineering
Field of Study
​Electrical Engineering, Computer science, physics, neurosciences
Division
Computer, Electrical and Mathematical Sciences and Engineering

Project Description

Diagnostics become more important in third world countries as the people have limited access to medical care systems and have less awareness of healthy lifestyles. There is certainly a need for on-site detection in the life science fields; and for point-of-care diagnostics in rural areas of underdeveloped countries so that even an unskilled person can use the device to determine the presence of disease-causing markers. Currently, diagnostics commonly employ long assay time, trained personnel, sophisticated instruments, and require financial support. A good approach to overcome this current situation would be the use of flexible and paper-based point-of-care devices to detect specific biomarkers. Biomarkers provide insight into normal biological processes, pathogenic processes, and pharmacological therapeutic interventions. Hence, the development of more compatible, reliable, convenient, simple, easyto- use systems would be of great use to a person less skilled in medical diagnostic procedures.​​​​​

About the Researcher

Khaled Nabil Salama
Professor, Electrical and Computer Engineering
Computer, Electrical and Mathematical Science and Engineering Division

Affiliations

Education Profile

  • Ph.D. Electrical Engineering, Stanford University, Palo Alto, CA, United States, 2005
  • M.S. Stanford University, Palo Alto, CA, U.S., 2000
  • B.S. Cairo University, Egypt, 1997

Research Interests

a€‹Professor Salama's research interests cover a variety of interdisciplinary aspects of electronic circuit design and semiconductors' fabrication. He is engaged in developing devices, circuits, systems, and algorithms to enable inexpensive analytical platforms for a variety of industrial, environmental, and biomedical applications. Recently he has been working on neuromorphic circuits for brain emulation.

Selected Publications

  • Y. Lei, W. Zhao, Y. Zhang, Q. Jiang, J. H. He, A. J. Baeumner, O. Wolfbeis, Z. L. Wang, K. N. Salama, H. N. Alshareef, ""A MXene-Based Wearable Biosensor System for High-Performance In Vitro Perspiration Analysis,"" Small 1901190 (2019).
  • EloA¯se Bihar, Shofarul Wustoni, Anna Maria Pappa, Khaled N. Salama, Derya Baran and Sahika Inal, A fully inkjet-printed disposable glucose sensor on paper, npj Flexible Electronics, 2, 1, (2018). 10.1038/s41528-018-0044-y
  • Rafiq Ahmada , Otto S. Wolfbeisa , Yoon-Bong Hahna , Husam N. Alshareefa , Luisa Torsia  and Khaled N. Salamaa  ""Deposition of nanomaterials: A crucial step in biosensor fabrication,"" Materials Today Communications, Vol. 17, pp. 289-321, 2018. doi:10.1016/j.mtcomm.2018.09.024
  • Saurabh Kumar, Yongjiu Lei, Niman H. Alshareef, M.A. Quevedo-Lopez, Khaled N. Salama ""Biofunctionalized Two-Dimensional Ti3C2 MXenes for Ultrasensitive Detection of Cancer Biomarker"", Biosensors and Bioelectronics, Vol 121, pp 243-249, 2018 DOI: 10.1016/j.bios.2018.08.076
  • Rafiq Ahmad, Tutku BedA¼k, Sanjit Manohar Majhi and Khaled Nabil Salama, One-step synthesis and gold nanoparticle decoration of nickel oxide nanosheets for hydrazine sensing application, Sensors & Actuators: B. Chemical, Vol. 286, pp139-147, 2019 https://doi.org/10.1016/j.snb.2019.01.132
  • Sandeep G.Surya, Harshil N.Raval, RafiqAhmad, PrashantSonar, Khaled N.Salama, V.Ramgopal Rao, Organic field effect transistors (OFETs) in environmental sensing and health monitoring: A review, Trends in Analytical Chemistry, vol 111, pp 27-36, 2019. https://doi.org/10.1016/j.trac.2018.11.027
  • Mohamed Tchalala, Prashant Bhatt, Karumbaiah Chappanda, SA©rgio Tavares, Karim Adil, Youssef Belmabkhout, Aleksander Shkurenko, Amandine Cadiau, Nicolas Heymans, Guy Deweireld, Guillaume Maurin, Khaled Nabil Salama, and Mohamed Eddaoudi, ""Fluorinated MOF platform for selective removal and sensing of SO2 from flue gas and air"" Nature Communications, vol10, no. 1328, 2019
  • Zhengyuan Zhou, Tiantian Kong, Hend Mkaouar, Khaled N.Salama and Jia Ming Zhang ""A hybrid modular microfluidic device for emulsion generation,"" Sensors and Actuators A: Physical, volume 280, pp 422-428, 2018 doi:10.1016/j.sna.2018.08.005

Desired Project Deliverables

​1-      A complete biosensor design and simulation  2-      Potential fully operational Hardware device  3-      Full detailed report on the design and participation in manuscript and papers writeup​